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Buruli Ulcer |
The cause of this disease is due to a toxin produced by bacteria called Mycobacterium ulcerans. Biting insects that dwell in swampy areas tend to carry the bacteria in their saliva, where they introduce the infection into unsuspecting hosts upon biting the skin.
The primary treatment methods include systemic antibiotics and surgery. Typical antibiotic regimens include streptomycin and rifampin for 8 weeks duration. Clarithromycin has been substituted for streptomycin with success in the past. For ulcers that are larger or do not respond to antibiotics, surgery may be considered.
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