Buruli ulcer is a skin infection typically found in regions of Australia, Africa, Asia, Mexico, and South America. The disease traditionally presents as a single painless nodule under the skin’s surface and swelling in this region may or may not be present. Fever may accompany disease forms where diffuse swelling is present. In the absence of treatment, the lesion may progress into an ulcer where underlying structures such as muscle or tendons could become exposed. If the disease reaches this stage, the infection may spread to the deeper surrounding organs or bones. Disfiguring scars are not uncommon in the absence of treatment. Buruli ulcer tends to favor the arms and legs. A greater risk of infection exists for both children and the elderly.

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