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Granuloma Inguinale |
Diagnosis of granuloma inguinale is not an easy task, since the organism that causes the infection is very difficult to grow on a culture medium. The most common method of diagnosis is through direct visualization of the organism. Smears are taken from the base of the ulcer and then visualized directly under a microscope. Scientists will then look for characteristic "Donovan bodies” on the slide. The antibiotic of choice for treating granuloma inguinale is either trimethoprim-sulfamethoxazole(TMP-SMX) or doxycycline. Other possible antibiotic options include erythromycin or ciprofloxacin. Treatment should last for at least 21 days (3 weeks) and continued until all signs of disease are gone. Special consideration is given to pregnant women infected with Klebsiella granulomatosis. The Centers for Disease Control (CDC) suggests using erythromycin, instead of TMP-SMX or doxycycline, due to its safety profile during pregnancy. All sexual partners who have had contact with the infected individual within 60 days of the onset of symptoms should also be treated.
The medical information provided in this site is for educational purposes only and is the property of the American Osteopathic College of Dermatology. It is not intended nor implied to be a substitute for professional medical advice and shall not create a physician - patient relationship. If you have a specific question or concern about a skin lesion or disease, please consult a dermatologist. Any use, re-creation, dissemination, forwarding or copying of this information is strictly prohibited unless expressed written permission is given by the American Osteopathic College of Dermatology. |
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