Orange palpebral spots (OPS) are a recently recognized condition first reported in 2008. These lesions are asymptomatic, yellow-orange oval macules that lie symmetrically over the inner portion of the upper eyelids. From the cases reported, OPS mostly appear in middle-aged women with fair skin.
Although the cause of OPS remains unknown, there are a few factors that play a role in the presentation of these lesions. When examined under a microscope, there was found scattered fat cells in the upper portion of skin. The skin may also have an increased of the colored pigments carotenoids and lipofuscin. Since the eyelids are one of the thinnest areas of skin on the body, fat cells and pigment are easier to be seen. An additional theory is that the pigment is a result of local trauma: rubbing and excessive blinking. Yet, there is much more research needed to identify the actual cause.
Treatment of OPS is not necessary due to the benign nature of these lesions.
Back to Index
The medical information provided in this site is for educational purposes only and is the property of the American Osteopathic College of Dermatology. It is not intended nor implied to be a substitute for professional medical advice and shall not create a physician - patient relationship. If you have a specific question or concern about a skin lesion or disease, please consult a dermatologist. Any use, re-creation, dissemination, forwarding or copying of this information is strictly prohibited unless expressed written permission is given by the American Osteopathic College of Dermatology.